G-protein βγ subunits as multi-functional scaffolds and transducers in G-protein-coupled receptor signaling
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چکیده
منابع مشابه
G-protein Coupled Receptor Dimerization
A growing body of evidence suggests that GPCRs exist and function as dimers or higher oligomers. The evidence for GPCR dimerization comes from biochemical, biophysical and functional studies. In addition, researchers have shown the occurrence of heterodimerization between different members of the GPCR family. Two receptors can interact with each other to make a dimer through their extracellular...
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Uptake through the Dopamine Transporter (DAT) is the primary mechanism of terminating dopamine signaling within the brain, thus playing an essential role in neuronal homeostasis. Deregulation of DAT function has been linked to several neurological and psychiatric disorders including ADHD, schizophrenia, Parkinson's disease, and drug addiction. Over the last 15 years, several studies have reveal...
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ژورنال
عنوان ژورنال: Cellular and Molecular Life Sciences
سال: 2019
ISSN: 1420-682X,1420-9071
DOI: 10.1007/s00018-019-03275-2